Long-term issues such as social healthcare costs, short-term issues such as the development and stable supply of drugs, and advanced technological issues such as regenerative medicine and personalized medicine - in order to tackle these issues, methodologies are required to rethink and redefine the ideal state of med & pharma. In this symposium, we will discuss the role of systems approaches to pharmaceuticals, with overviewing the latest research at the cellular, process, and societal levels. In particular, this year's symposium will deepen the discussion on the interconnections of the systems across temporal and spatial scales.